Knowledge Management System Of Qinghai Institute of Salt Lakes,CAS
| Nanomanipulation of Individual DNA Molecules Covered by Single-Layered Reduced Graphene Oxide Sheets on a Solid Substrate | |
Wang, Ying; Shen, Yue ; Li, Bin; Wang, Shuo; Zhang, Jinjin; Zhang, Yi; Hu, Jun
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| 第一作者 | Wang, Ying |
| 2018-01-18 | |
| 发表期刊 | JOURNAL OF PHYSICAL CHEMISTRY B
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| ISSN | 1520-6106 |
| 卷号 | 122期号:2页码:612-617 |
| 摘要 | Nanomanipulation of single DNA molecules has great potential in fundamental genetic research and clinical analysis, and is a good model system for studying the interfacial effects on physiochemical processes, which occur when manipulating the linear DNA molecules with an atomic force microscope (AFM) tip. Here, we demonstrate that AFM nanomanipulation can be carried out on DNA molecules covered by a single-layered reduced graphene oxide sheet. Nanomanipulation, which includes cutting, pushing, and sweeping operations, specific to the covered DNA molecules can be achieved in a well-controlled manner using AFM in the PeakForce Quantitative Nano-Mechanics mode. It was found that the normal force required to cut covered DNA strands is over five times greater than that required for naked strands. This technique provides a distinctive method for the construction of graphene architecture by tailoring the underlying artificial DNA nanostructures. |
| DOI | 10.1021/acs.jpcb.7b05175 |
| 语种 | 英语 |
| 引用统计 | |
| 文献类型 | 期刊论文 |
| 条目标识符 | http://ir.isl.ac.cn/handle/363002/6414 |
| 专题 | 青海盐湖研究所知识仓储 盐湖资源与化学实验室 |
| 推荐引用方式 GB/T 7714 | Wang, Ying,Shen, Yue,Li, Bin,et al. Nanomanipulation of Individual DNA Molecules Covered by Single-Layered Reduced Graphene Oxide Sheets on a Solid Substrate[J]. JOURNAL OF PHYSICAL CHEMISTRY B,2018,122(2):612-617. |
| APA | Wang, Ying.,Shen, Yue.,Li, Bin.,Wang, Shuo.,Zhang, Jinjin.,...&Hu, Jun.(2018).Nanomanipulation of Individual DNA Molecules Covered by Single-Layered Reduced Graphene Oxide Sheets on a Solid Substrate.JOURNAL OF PHYSICAL CHEMISTRY B,122(2),612-617. |
| MLA | Wang, Ying,et al."Nanomanipulation of Individual DNA Molecules Covered by Single-Layered Reduced Graphene Oxide Sheets on a Solid Substrate".JOURNAL OF PHYSICAL CHEMISTRY B 122.2(2018):612-617. |
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| Nanomanipulation of （6002KB） | 期刊论文 | 出版稿 | 开放获取 | CC BY-NC-SA | 浏览 请求全文 | |
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